21+
Age Verification
You must be 21 years of age or older to enter this site.
By entering, you confirm you are 21 years of age or older.
You must be 21 years of age or older to enter this site.
By entering, you confirm you are 21 years of age or older.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. With a molecular weight of 711.85 Da (CAS: 170851-70-4), this five-amino-acid peptide selectively interacts with the growth hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor. Its compact molecular structure and high receptor selectivity have made it a widely studied compound in peptide research.
Published preclinical studies have characterized Ipamorelin as one of the most selective GHS-R1a agonists identified to date. Unlike earlier generation secretagogues, in-vitro binding assays demonstrate that Ipamorelin exhibits minimal cross-reactivity with ACTH, cortisol, or prolactin signaling pathways. This selectivity profile has made it a preferred research tool for investigating isolated GH-axis signaling without confounding hormonal variables.
AXOM Ipamorelin is manufactured under strict cGMP-equivalent protocols and verified to ≥99% purity via reverse-phase HPLC. Each lot is accompanied by a Certificate of Analysis documenting identity, purity, peptide content, and endotoxin levels. Available in 10mg lyophilized format. For research and laboratory use only.
Exhibits high selectivity for the ghrelin receptor (GHS-R1a) with minimal cross-reactivity in ACTH and cortisol pathways, enabling clean in-vitro signaling studies.
5-amino acid sequence incorporating non-natural residues (Aib, D-2-Nal, D-Phe) for enhanced receptor binding affinity and metabolic stability in research assays.
≥99% HPLC-verified purity with full COA documentation. Every lot independently tested by third-party analytical laboratories.
Foundational study characterizing Ipamorelin as the first selective GHS-R1a agonist. Demonstrated through in-vitro receptor binding assays that Ipamorelin stimulates GH release without affecting ACTH, cortisol, prolactin, or FSH/LH signaling in preclinical models.
Comprehensive review of growth hormone secretagogue research, including detailed comparison of Ipamorelin's binding profile against earlier-generation GHS compounds. Discusses receptor pharmacology, structure-activity relationships, and in-vitro assay methodologies.
Detailed characterization of GHS-R1a intracellular signaling cascades relevant to Ipamorelin mechanism of action. Examines G-protein coupling, calcium mobilization, and downstream MAPK pathway activation in cell-based assay systems.
| Product Name | Ipamorelin |
| Synonyms | Ipamorelin, NNC 26-0161 |
| CAS Number | 170851-70-4 |
| Molecular Formula | C38H49N9O5 |
| Molecular Weight | 711.85 Da |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| Sequence Length | 5 amino acids (pentapeptide) |
| Classification | Growth Hormone Secretagogue (GHS-R1a agonist) |
| Purity | ≥99% (Reverse-Phase HPLC) |
| Form | Lyophilized white powder |
| Available Sizes | 10mg |
| Solubility | Soluble in sterile water, bacteriostatic water |
| Endotoxin | <1 EU/μg (LAL method) |
| Certification | COA included with every order |
| Intended Use | For research and laboratory use only |
Ipamorelin is supplied as a lyophilized powder and should be reconstituted with sterile bacteriostatic water (BAC water) for research applications.
All orders ship within the continental United States via USPS or UPS. Peptides are shipped at ambient temperature — lyophilized peptides are stable during transit. Free shipping on orders over $250.
