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GLP Peptides

GLP3-RT

Retatrutide — Triple Agonist Research Compound
Concentration
In Stock

GLP3-RT is a synthetic 39-amino acid triple receptor agonist (GIP/GLP-1/Glucagon) supplied as ≥99% HPLC-verified lyophilized powder. For research use only.

Quantity
1
Vial
$89.99
$89.99 / vial
Save 17%
2
Vials
$161.98
$81.00 / vial
You save $18.00
Save 26%
3
Vials
$229.47
$76.49 / vial
You save $40.50
≥99% Purity
cGMP Certified
3-Day Delivery
GLP3-RT
GLP3-RT
10mg • 1 Vial
Save 17%
Save 26%
Triple Agonist

Targets GIP, GLP-1, and glucagon receptors simultaneously

≥99% HPLC Purity

Every lot independently verified by third-party laboratories

COA Included

Full Certificate of Analysis with HPLC, mass spec, and endotoxin data

What is GLP3-RT?

GLP3-RT is a synthetic 39-amino acid peptide that functions as a triple receptor agonist, engaging GIP, GLP-1, and glucagon receptors simultaneously in a single molecular entity. This tri-agonist mechanism represents the next generation of incretin-based research compounds.

Featuring a C20 fatty diacid moiety conjugated via a linker to lysine at position 17, this compound enables extended pharmacokinetic profiles in preclinical models. GLP3-RT has been the subject of multiple peer-reviewed Phase I and Phase II clinical studies evaluating its receptor binding characteristics.

Each lot is manufactured under strict cGMP-equivalent protocols and verified to ≥99% purity via reverse-phase HPLC analysis. A full Certificate of Analysis documenting identity, purity, peptide content, and endotoxin levels is included with every order.

Supplied as a lyophilized white powder, available in 10mg and 20mg formats. Soluble in sterile water and bacteriostatic water. For research and laboratory use only.

Specifications

CAS Number 2381089-83-2
Molecular Weight ~4,113.58 Da
Sequence 39 amino acids
Targets GIP / GLP-1 / Glucagon
Purity ≥99% (HPLC)
Form Lyophilized powder
Storage -20°C (lyophilized)
Endotoxin <1 EU/μg
Published Research

Peer-Reviewed Studies

Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a phase 2 trial Rosenstock J, et al. • The Lancet, 2023
Triple hormone receptor agonist retatrutide for metabolic dysfunction: a phase 2 trial Jastreboff AM, et al. • NEJM, 2023
LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist: a phase 1b multiple-ascending study Coskun T, et al. • The Lancet, 2022
Common Questions

GLP3-RT FAQ

GLP3-RT is a synthetic 39-amino acid peptide that functions as a triple agonist, targeting GIP, GLP-1, and glucagon receptors simultaneously. It is intended exclusively for in-vitro and laboratory research applications.

Verified at ≥99% purity via reverse-phase HPLC. Each lot includes mass spectrometry confirmation and endotoxin testing. Full COA included with every order.

Lyophilized: -20°C long-term, stable at 2–8°C for 90 days. Reconstituted: 2–8°C, use within 28 days. Protect from light.

Yes. Every order includes a lot-specific COA with HPLC chromatography, mass spec data, peptide content, and endotoxin levels.

Orders before 2PM EST ship same day. Standard delivery is 2–4 business days within the continental US. All orders include tracking.

Yes. Select 2 or 3 vials on any product page for automatic volume pricing. For larger orders, contact support@axomresearch.com.

Still have questions about GLP3-RT or any of our research compounds?

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