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Peptides

IGF-1 LR3

Insulin-Like Growth Factor-1 Long R3 — Cell Proliferation Research Compound
In Stock

IGF-1 LR3 is a modified 83-amino acid analog of insulin-like growth factor-1 with extended half-life, studied for cell proliferation and growth signaling research. ≥99% HPLC-verified. For research use only.

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1
Vial
$124.99
$124.99 / vial
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2
Vials
$219.99
$110.00 / vial
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3
Vials
$299.99
$100.00 / vial
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≥99% Purity
cGMP Certified
3-Day Delivery
IGF-1 LR3
IGF-1 LR3
1mg • 1 Vial
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Save 20%
83-Amino Acid Analog

Modified IGF-1 with Arg³ substitution and 13-amino acid extension

≥99% HPLC Purity

Every lot independently verified by third-party laboratories

COA Included

Full Certificate of Analysis with HPLC, mass spec, and endotoxin data

What is IGF-1 LR3?

IGF-1 LR3 is a modified form of insulin-like growth factor 1, featuring an arginine substitution at position 3 and a 13-amino acid N-terminal extension peptide, totaling 83 amino acids. These modifications significantly reduce binding to IGF-binding proteins.

Published research has examined IGF-1 LR3's enhanced receptor binding characteristics and extended biological activity compared to native IGF-1 in cell culture and preclinical models.

Manufactured under cGMP-equivalent protocols and verified to ≥99% purity via HPLC. Full COA included with every order.

Supplied as a lyophilized white powder. Soluble in sterile water and bacteriostatic water. For research and laboratory use only.

Specifications

CAS Number 946870-92-4
Molecular Weight ~9,111 Da
Sequence 83 amino acids
Modification Arg³ + 13-aa N-term extension
Purity ≥99% (HPLC)
Form Lyophilized powder
Storage -20°C (lyophilized)
Endotoxin <1 EU/μg
Published Research

Peer-Reviewed Studies

Long R3 IGF-I: biological activity and potency in cell culture models Francis GL, et al. • J Endocrinol, 1992
Insulin-like growth factors and their binding proteins: biological actions Jones JI, et al. • Endocr Rev, 1995
IGF-I signaling pathways and cellular responses LeRoith D, et al. • Endocr Rev, 2001
Common Questions

IGF-1 LR3 FAQ

IGF-1 LR3 is a modified 83-amino acid analog of insulin-like growth factor 1 with reduced binding protein affinity. It is intended exclusively for in-vitro and laboratory research.

Verified at ≥99% purity via reverse-phase HPLC. Each lot includes mass spectrometry confirmation and endotoxin testing. Full COA included.

Lyophilized: -20°C long-term, stable at 2–8°C for up to 30 days. Reconstituted: 2–8°C, use within 14 days. Protect from light.

Yes. Every order includes a lot-specific COA with HPLC chromatography, mass spec data, peptide content, and endotoxin levels.

Orders before 2PM EST ship same day. Standard delivery is 2–4 business days within the continental US. All orders include tracking.

Still have questions about IGF-1 LR3 or any of our research compounds?

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