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Selank is a synthetic heptapeptide analogue of the naturally occurring immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg). Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank extends the native tuftsin sequence with a C-terminal Pro-Gly-Pro tripeptide, resulting in the full sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. This structural modification confers enhanced metabolic stability compared to the parent compound.
The compound has been extensively characterized in published preclinical literature. Selank's heptapeptide structure incorporates the complete tuftsin pharmacophore while the Pro-Gly-Pro extension provides resistance to enzymatic degradation by aminopeptidases, resulting in a prolonged activity profile observed in in-vitro stability assays. The peptide has been the subject of multiple peer-reviewed studies examining its receptor binding characteristics and downstream signaling pathways.
AXOM Selank is manufactured under strict cGMP-equivalent protocols and verified to ≥99% purity via reverse-phase HPLC. Each lot is accompanied by a Certificate of Analysis documenting identity, purity, peptide content, and endotoxin levels. Available in 5mg and 10mg lyophilized formats. For research and laboratory use only.
Synthetic analogue of the naturally occurring immunomodulatory tetrapeptide tuftsin, extended with a stabilizing Pro-Gly-Pro C-terminal sequence for enhanced research utility.
Seven-amino-acid sequence (Thr-Lys-Pro-Arg-Pro-Gly-Pro) with well-characterized structure and documented enhanced metabolic stability versus native tuftsin.
≥99% HPLC-verified purity with full COA documentation. Every lot independently tested by third-party analytical laboratories.
Comprehensive pharmacological profile of Selank examining the heptapeptide's receptor binding characteristics, metabolite identification, and downstream signaling pathway engagement. Documents the compound's interaction with multiple peptidase systems and characterizes the activity profiles of primary and secondary metabolic fragments.
In-vitro and in-vivo study examining Selank's influence on gene expression patterns associated with GABAergic signaling pathways. The research provides quantitative mRNA expression data for key receptor subtypes following peptide exposure in controlled experimental models.
Study characterizing Selank's effects on chemokine and cytokine gene expression profiles in peripheral blood mononuclear cell cultures. Provides transcriptomic data demonstrating the tuftsin analogue's modulatory activity on immune-related gene networks in standardized in-vitro assay conditions.
| Product Name | Selank (Tuftsin Analogue) |
| Synonyms | TP-7, Selanc |
| CAS Number | 129954-34-3 |
| Molecular Formula | C33H57N11O9 |
| Molecular Weight | ~751.87 Da |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (7 amino acids) |
| Parent Peptide | Tuftsin (Thr-Lys-Pro-Arg) + Pro-Gly-Pro extension |
| Purity | ≥99% (Reverse-Phase HPLC) |
| Form | Lyophilized white powder |
| Available Sizes | 5mg, 10mg |
| Solubility | Soluble in sterile water, bacteriostatic water |
| Endotoxin | <1 EU/μg (LAL method) |
| Certification | COA included with every order |
| Intended Use | For research and laboratory use only |
Selank is supplied as a lyophilized powder and should be reconstituted with sterile bacteriostatic water (BAC water) for research applications.
All orders ship within the continental United States via USPS or UPS. Peptides are shipped at ambient temperature — lyophilized peptides are stable during transit. Free shipping on orders over $250.
